Regulatory questions, answered.
Questions asked in RegAffairs AI and answered from official sources, with every claim cited to the document it came from.
Skin lightening creams sold in the UK: which ingredients (hydroquinone, mercury, corticosteroids such as clobetasol) are prohibited or restricted in cosmetics under the UK Cosmetics Regulation (Schedule 34 to the Product Safety and Metrology etc. (Amendment etc.) (EU Exit) Regulations 2019, Annexes II and III), what recent OPSS product safety alerts and recalls say about skin lightening products, and what an importer or retailer must check to sell a compliant product?
Under the GB Cosmetics Regulation, none of these three can be used to lighten skin.
Qual è la definizione di malattia professionale nell'ordinamento italiano (DPR 1124/1965, INAIL)? Differenza rispetto all'infortunio sul lavoro, malattie tabellate e non tabellate, sistema misto, esempi e dati INAIL sulle denunce.
Nell'ordinamento italiano la malattia professionale è la patologia che il lavoratore contrae a causa dell'attività lavorativa, cioè per l'esposizione nel…
Comment rechercher un produit phytopharmaceutique dans E-Phy (ANSES) : numéro d'AMM, usages autorisés et doses, statut de retrait, par exemple Kerb Flo, Teppeki et Amistar ?
Kerb Flo (AMM 8400574), Teppeki (AMM 2050046) et Amistar (AMM 9600093) sont tous trois autorisés (AUTORISE) dans E-Phy.
トルエンは毒物及び劇物取締法上の劇物に該当しますか？指定令の該当号と濃度による除外の有無、メタノール、キシレン、アセトニトリル、クロロホルム、メチルエチルケトンについても該当条件を教えてください。
トルエンは劇物です。 毒物及び劇物指定令第2条第1項第76号の2に「トルエン」とだけ書かれており、「及びこれを含有する製剤」の文言はありません。条文上は物質そのもの（原体）だけが指定されているので、トルエンを含む製剤はこの号では劇物になりません。濃度による除外の規定もありません。6物質のうち濃度の線引きがあるのはアセ…
How is a surface disinfectant containing didecyldimethylammonium chloride (DDAC) regulated in the EU, Spain and the US: active substance approval status by product type, the authorisation route, and the relevant register entries?
Summary: In the EU, DDAC (EC 230-525-2, CAS 7173-51-5) is an approved active substance for PT2, the product type that covers surface disinfectants.
A textile is treated with a silver-based antimicrobial. Under the EU Biocidal Products Regulation, what does Article 58 require for this treated article (approval of the active substance for the right product type, labelling), and is silver zinc zeolite approved for product type 9?
Yes. Silver zinc zeolite (EC 603-404-0, CAS 130328-20-0) is approved for PT09 (fibre, leather, rubber and polymerised materials preservatives).
What is the EU approval status of permethrin under the Biocidal Products Regulation (EU) 528/2012: for which product types is it approved, when do the approvals expire, and what conditions apply to products containing it?
Permethrin (EC 258-067-9, CAS 52645-53-1) is approved under the BPR for two product types: PT08 (wood preservatives) and PT18 (insecticides, acaricides and…
Is salicylic acid allowed in leave-on cosmetics in the EU, the UK, Canada, South Korea and Japan? Give the maximum concentration, product types and required warnings in each market, citing each market's official list.
Yes, salicylic acid is allowed in leave-on cosmetics in all five markets, but the limits differ a lot.
What are the EU rules for retinol and retinyl esters in cosmetics after Commission Regulation (EU) 2024/996: Annex entry, maximum concentrations by product type, warnings, transition dates, and what the SCCS concluded?
Commission Regulation (EU) 2024/996 added a new Annex III entry, reference number 376, to Regulation (EC) No 1223/2009.
What rules apply to drawstrings and cords on children's clothing in the US, Canada, the UK and the EU, and which recalls or market surveillance alerts have regulators issued for children's hoodies and jackets with drawstrings?
All four jurisdictions treat cords and drawstrings at the hood and neck of children's outerwear as a strangulation hazard.
Which REACH Annex XVII restrictions apply to chemicals in clothing, textiles, leather and footwear sold in the EU? List each entry (for example azo dyes, chromium VI in leather, nickel, DMF, PAHs, nonylphenol ethoxylates and the CMR substances in textiles), the limit values and the dates they apply.
Answer: Under REACH Annex XVII, the restrictions that apply directly to clothing, textiles, leather and footwear on the EU market are entries 4, 7, 8, 20, 27…
What must a fibre content label on clothing show in the US (Textile Fiber Products Identification Act, 16 CFR 303), the EU (Regulation 1007/2011) and Canada (Textile Labelling Act)? Compare fibre names, percentages, tolerances, dealer identity numbers (RN, CA number) and language rules.
All three require fibre names and percentages by weight, but they differ on the details.
What are the maximum residue limits (MRLs) for acetamiprid on apples and on table grapes in the EU, the US, Codex, Japan and South Korea? Give each value with its legal source and date, and note any recent EU change.
I found apple and table-grape MRLs for acetamiprid in four of the five jurisdictions; I couldn't confirm a Japanese value from an official source.
What is the EU approval status of flufenacet under Regulation (EC) 1107/2009: was it renewed, what are the dates for withdrawing authorisations and the grace periods for sale and use of existing stocks, and what does this mean for products authorised in Germany and France?
Flufenacet was not renewed. Commission Implementing Regulation (EU) 2025/910 of 20 May 2025 refused renewal, and the EU Pesticides Database shows it as "Not…
Is paraquat allowed as a pesticide in Brazil, the EU, the UK and the US? Give the current status, the decision behind it and the date in each market, with citations.
Paraquat is allowed as a pesticide only in the US, where it remains registered under a 2021 interim decision with ongoing registration review.
Is PFHxA (CAS 307-24-4) restricted under REACH Annex XVII? Give the entry number, the uses covered, the concentration limits and the application dates, with citations.
Yes. PFHxA is restricted under REACH Annex XVII entry 79, "Undecafluorohexanoic acid (PFHxA), its salts and PFHxA-related substances".
Which national chemical inventories list formaldehyde (CAS 50-00-0)? Check the EU (EC number), US TSCA, Canada DSL, Australia AICIS, Japan ENCS, Korea KECI, China IECSC and Turkey KKDIK, with citations for each.
Formaldehyde (CAS 50-00-0) is listed in all eight jurisdictions you named.
What is the current harmonised classification and labelling of titanium dioxide (CAS 13463-67-7) under CLP Annex VI, and what changed after the EU General Court and Court of Justice rulings? Give the entry, hazard classes and dates, with citations.
There is no harmonised CLP classification for titanium dioxide (CAS 13463-67-7) in force today.
What are the occupational exposure limits for formaldehyde in the EU, Germany, the UK and the US (OSHA)? Give the 8-hour and short-term values, the legal source and the date each applies from, with citations.
Formaldehyde (CAS 50-00-0) limits: the EU and Germany have the same values, 0.3 ppm (0.37 mg/m³) over 8 hours and 0.6 ppm (0.74 mg/m³) short-term.
What are the reporting thresholds for ammonia releases to air from an industrial facility under the EU Industrial Emissions Portal Regulation (E-PRTR), Canada's NPRI and the US Toxics Release Inventory (TRI)? Cite each threshold.
Only the EU sets a threshold on the ammonia actually released to air: 10,000 kg/year.